Harvard Health Columns

Finding the right depression medication

STAR*D results still provide useful guidance In spite of the variety of medication options now available, major depression remains a challenging disease to treat. Only about half of adult patients respond to the first antidepressant prescribed, with only one-third achieving remission. When symptoms are not adequately relieved by the first antidepressant, patients and their clinicians face a difficult decision. Although two broad strategies exist switching to a new drug or augmenting…

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