Harvard Health Tips
Pseudoephedrine and blood pressure
A medication called pseudoephedrine, found in many over-the-counter cough and cold remedies, constricts blood vessels in the nose and sinuses, which decreases swelling and drains fluids. Unfortunately, the drug doesn't affect only the head — it tightens blood vessels throughout the body, which can sometimes increase blood pressure. If you have high blood pressure or heart disease, don't take medications that contain pseudoephedrine.