Harvard Health Beat

Cholesterol-lowering medications: PCSK9 inhibitors

In the summer of 2015, the FDA approved two new cholesterol- lowering drugs, alirocumab (Praluent) and evolocumab (Repatha). They belong to a novel category of medications called PCSK9 inhibitors. To understand what these drugs are and how they work, it's helpful to know a little bit about PCSK9 and why you might want to inhibit it. PCSK9 is a protein that targets and breaks down a certain class of receptors in the liver. Those…

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