Harvard Heart Letter

Statins may offer a long-term legacy benefit

Cholesterol-lowering statins seem to have long-lasting benefits against heart disease, according to a 20-year follow-up of a landmark Scottish study. In the original study, published in 1995, more than 6,500 middle-aged men with high levels of harmful LDL cholesterol took either 40 milligrams of pravastatin (Pravachol) or a placebo daily for an average of nearly five years. For the follow-up, published in the March 15 Circulation, researchers used electronic medical records to analyze…

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