Harvard Women's Health Watch
Is a heartburn drug hurting your health?
Long-term risks are associated with proton-pump inhibitors, but there are other options for treating acid reflux. Proton-pump inhibitors (PPIs), which reduce the amount of acid produced in the stomach, are so effective at treating heartburn and ulcers that they’ve been among the world’s top-selling drugs for 25 years. Initially available only by prescription, PPIs, which include omeprazole (Prilosec), lansoprazole (Prevacid), and esomeprazole (Nexium), have been sold over the counter for several years.