Harvard Health Blog
More opioids, more pain: Fueling the fire
More opioids, more pain: Fueling the fire By: Shafik Boyaji, MD, Contributor, and David Boyce, MD, Contributor For more than a century, clinicians have noticed a paradoxical phenomenon: certain patients who are taking opioids (which are supposed to numb pain) become more sensitive to pain than those who are not taking opioids.